Trimethylglycine (TMG) is a molecule derived from the amino acid glycine, crucial for various bodily functions. It supports methylation, a process influencing gene expression, cell repair, and toxin removal. TMG benefits include enhanced heart health by regulating homocysteine levels, liver protection from alcohol and non-alcoholic fatty liver disease, and cognitive support by protecting brain cells and enhancing neurotransmitter production. Additionally, TMG improves muscle endurance, demonstrated in studies where participants showed better exercise performance with TMG supplementation. TMG also helps reduce the risk of dementia by improving memory, maintaining nerve cell connections, and reducing harmful brain reactions. Taking TMG alongside NAD boosters can create a synergistic effect, enhancing overall cellular energy and health.